New Therapeutic Target Discovered to Aid in Glaucoma Treatment: CIB2 Protein Regulating Calcium Ion Flow in the Eye
Therapeutic Target Discovered to Aid in Glaucoma Treatment
- Glaucoma is a condition where the optic nerve is damaged leading to vision loss
- The condition is caused by high intraocular pressure (IOP) in the eye
- Researchers have discovered a therapeutic target that could aid in treating glaucoma
- The target is a protein called CIB2 which regulates the flow of calcium ions in the eye
- The researchers found that CIB2 levels were lower in the eyes of glaucoma patients compared to healthy individuals
- By increasing CIB2 levels in the eye, the researchers were able to reduce IOP in a mouse model of glaucoma
- The findings suggest that targeting CIB2 could be a potential therapeutic strategy for glaucoma treatment
- The study was conducted by researchers at the University of California, San Diego, and was published in the journal PNAS
- The study was carried out on mice, and further research is needed to determine if the findings will apply to humans as well
- Glaucoma affects more than 60 million people worldwide and is a leading cause of blindness
- Current treatments for glaucoma focus on reducing IOP, but many patients still experience vision loss despite treatment
